Pupilla di argyll robertson

Argyll Robertson pupil

pupilla di argyll robertson

Argyll Robertson pupils are bilateral small pupils that reduce in size on a near object (i.e., they accommodate), but do not constrict when exposed to bright light .

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Adie syndrome also known as the Holmes-Adie syndrome is a neurological disorder characterized by a tonically dilated pupil that reacts slowly to light but shows a more definite response to accommodation i. It is named after the British neurologists William John Adie and Gordon Morgan Holmes who independently described the same disease in Adie syndrome presents with three hallmark symptoms, namely at least one abnormally dilated pupil mydriasis which does not constrict in response to light, loss of deep tendon reflexes, and abnormalities of sweating. Pupillary symptoms of Holmes—Adie syndrome are thought to be the result of a viral or bacterial infection that causes inflammation and damage to neurons in the ciliary ganglion , located in the posterior orbit, that provides parasympathetic control of eye constriction. Additionally, patients with Holmes-Adie Syndrome can also experience problems with autonomic control of the body. This second set of symptoms is caused by damage to the dorsal root ganglia of the spinal cord. Adie's pupil is supersensitive to ACh so agonist like pilocarpine whose dose would not be able to cause pupil constriction in normal patient would cause it in this patient.

Adie syndrome, or Holmes-Adie syndrome, is a rare neurological disorder affecting the pupil of the eye. In most patients the pupil is larger than normal dilated and slow to react in response to direct light. Absent or poor tendon reflexes are also associated with this disorder. In most individuals, the cause is unknown idiopathic , but Adie syndrome can occur as due to other conditions such as trauma, surgery, lack of blood flow ischemia or infection. In rare cases localized disturbance of sweat secretion is associated with Adie syndrome Ross syndrome. Adie syndrome involves a usually non progressive and limited damage to the autonomic nervous system, which is the portion of the nervous system that controls or regulates certain involuntary body functions including the reaction of the pupils to stimuli.



Adie syndrome

Argyll Robertson pupils AR pupils or, colloquially, " prostitute's pupils " are bilateral small pupils that reduce in size on a near object i. They are a highly specific sign of neurosyphilis ; however, Argyll Robertson pupils may also be a sign of diabetic neuropathy.,

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